Regorafenib induces NOX5-mediated endoplasmic reticulum stress and potentiates the anti-tumor activity of cisplatin in non-small cell lung cancer cells
Lung cancer is one of the most commonly diagnosed cancers worldwide. Although cisplatin-based chemotherapy regimens serve a pivotal role in non-small cell lung cancer (NSCLC) treatment, drug resistance and serious side effects limited its further clinical application. Regorafenib, a small-molecule m...
Main Authors: | Hehuan Sui, Sisi Xiao, Suping Jiang, Siyuan Wu, Haizhen Lin, Liyuan Cheng, Lihua Ye, Qi Zhao, Yun Yu, Lu Tao, Feng-Ming Kong, Xiaoying Huang, Ri Cui |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-05-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558623000222 |
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