PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite

PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite

Abstract Background The airway epithelial barrier function is disrupted in the airways of asthmatic patients. Abnormal mitochondrial biogenesis is reportedly involved in the pathogenesis of asthma. However, the role of mitochondrial biogenesis in the airway barrier dysfunction has not been elucidate...

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Bibliographic Details
Main Authors: Tsutomu Saito, Tomohiro Ichikawa, Tadahisa Numakura, Mitsuhiro Yamada, Akira Koarai, Naoya Fujino, Koji Murakami, Shun Yamanaka, Yusaku Sasaki, Yorihiko Kyogoku, Koji Itakura, Hirohito Sano, Katsuya Takita, Rie Tanaka, Tsutomu Tamada, Masakazu Ichinose, Hisatoshi Sugiura
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Respiratory Research
Subjects:
Asthma
Airway barrier dysfunction
PGC-1α
House dust mite
Online Access:https://doi.org/10.1186/s12931-021-01663-6

Internet

https://doi.org/10.1186/s12931-021-01663-6

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