How accurate and statistically robust are catalytic site predictions based on closeness centrality?

<p>Abstract</p> <p>Background</p> <p>We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertices within a graph and edges connect vertices that are proximal in s...

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Bibliographic Details
Main Authors: Livesay Dennis R, Chea Eric
Format: Article
Language:English
Published: BMC 2007-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/153