CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion

<p>Abstract</p> <p>Background</p> <p>Cisplatin is more often used to treat ovarian cancer (OvCa), which provides modest survival advantage primarily due to chemo-resistance and up regulated anti-apoptotic machineries in OvCa cells. Therefore, targeting the mechanisms re...

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Bibliographic Details
Main Authors: Johnson Erica L, Singh Rajesh, Johnson-Holiday Crystal M, Grizzle William E, Partridge Edward E, Lillard James W, Singh Shailesh
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Journal of Ovarian Research
Online Access:http://www.ovarianresearch.com/content/3/1/15