Cell Squeeze: driving more effective CD8 T-cell activation through cytosolic antigen delivery

Cell Squeeze: driving more effective CD8 T-cell activation through cytosolic antigen delivery

Cell Squeeze is a novel technology that relies on temporarily disrupting the cell membrane to deliver cargo directly into the cytosol. This approach is applicable to a broad range of cell types (peripheral blood mononuclear cells, red blood cells, hematopoietic stem cells, etc.) and cargos (peptides...

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Bibliographic Details
Main Authors: J.C. Park, H. Bernstein, S. Loughhead, R. Zwirtes, J. Jennings, V. Nicolini, C. Klein, L.C. Deak, P. Umana, C. Trumpfheller, A. Sharei
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Immuno-Oncology and Technology
Subjects:
Cell Squeeze
therapeutic cancer vaccine
cell therapy
MHC class I antigen presentation
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018822000223

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http://www.sciencedirect.com/science/article/pii/S2590018822000223

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