Biological significance of local TGF-β activation in liver diseases

The cytokine transforming growth factor-β (TGF-β) plays a pivotal role in a diverse range of cellular responses, including cell proliferation, apoptosis, differentiation, migration, adhesion, angiogenesis, stimulation of extracellular matrix (ECM) synthesis, and downregulation of ECM degradation. TG...

Full description

Bibliographic Details
Main Authors: Hiromitsu eHayashi, Takao eSakai
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00012/full