Synthesis, Characterization and Antimicrobial Evaluation with DFT Study of New Two-Amino-4-(4-Chlorophenyl) Thiazole Derivatives
2-amino-4-(4-chloro phenyl)-1,3-thiazole (1) was synthesized by refluxing thiourea with para-chloro phenacyl bromide in absolute methanol. The condensation of amine compound (1) with phenylisothiocyanate in the presence of pyridine will produce 1-(4-(4-chlorophenyl)thiazol-2-yl)-3-phenylthiourea(...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
College of Pharmacy University of Baghdad
2018-06-01
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Series: | Iraqi Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/776 |