Differential binding of human and murine IgGs to catalytic and cell wall binding domains of Staphylococcus aureus peptidoglycan hydrolases

Differential binding of human and murine IgGs to catalytic and cell wall binding domains of Staphylococcus aureus peptidoglycan hydrolases

Abstract Staphylococcus aureus is an opportunistic pathogen causing high morbidity and mortality. Since multi-drug resistant S. aureus lineages are nowadays omnipresent, alternative tools for preventive or therapeutic interventions, like immunotherapy, are urgently needed. However, there are current...

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Main Authors: Min Wang, Sanne van den Berg, Yaremit Mora Hernández, Aafke Hinke Visser, Elias Vera Murguia, Dennis G.A.M. Koedijk, Channah Bellink, Hilde Bruggen, Irma A. J. M. Bakker-Woudenberg, Jan Maarten van Dijl, Girbe Buist
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93359-6

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https://doi.org/10.1038/s41598-021-93359-6

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