PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis

Summary: Extensive remodeling of the female mammary epithelium during development and pregnancy has been linked to cancer susceptibility. The faithful response of mammary epithelial cells (MECs) to hormone signaling is key to avoiding breast cancer development. Here, we show that lactogenic differen...

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Bibliographic Details
Main Authors: Sijia Ren, Feng Bai, Viviane Schnell, Clara Stanko, Muriel Ritsch, Tino Schenk, Emanuel Barth, Manja Marz, Bin Wang, Xin-Hai Pei, Holger Bierhoff
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723016558