Analyzing the role of cancer‐associated fibroblast activation on macrophage polarization

Analyzing the role of cancer‐associated fibroblast activation on macrophage polarization

Snail1 is a transcriptional factor required for cancer‐associated fibroblast (CAF) activation, and mainly detected in CAFs in human tumors. In the mouse mammary tumor virus‐polyoma middle tumor‐antigen (MMTV‐PyMT) model of murine mammary gland tumors, Snai1 gene deletion, besides increasing tumor‐fr...

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Bibliographic Details
Main Authors: Marina Bruch‐Oms, Rubén Olivera‐Salguero, Rocco Mazzolini, Beatriz delValle‐Pérez, Paula Mayo‐González, Ángel Beteta, Raúl Peña, Antonio García de Herreros
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Molecular Oncology
Subjects:
CAF
macrophage polarization
Prostaglandin E2
Snail1
TGFβ
Online Access:https://doi.org/10.1002/1878-0261.13454

Internet

https://doi.org/10.1002/1878-0261.13454

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