Boosting targeted genome editing using the hei-tag

Boosting targeted genome editing using the hei-tag

Precise, targeted genome editing by CRISPR/Cas9 is key for basic research and translational approaches in model and non-model systems. While active in all species tested so far, editing efficiencies still leave room for improvement. The bacterial Cas9 needs to be efficiently shuttled into the nucleu...

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Bibliographic Details
Main Authors: Thomas Thumberger, Tinatini Tavhelidse-Suck, Jose Arturo Gutierrez-Triana, Alex Cornean, Rebekka Medert, Bettina Welz, Marc Freichel, Joachim Wittbrodt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
Oryzias latipes
CRISPR
Cas
targeted genome editing
nuclear localization
base editing
Online Access:https://elifesciences.org/articles/70558

Internet

https://elifesciences.org/articles/70558

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