Discovery of CLEC2B as a diagnostic biomarker and screening of celastrol as a candidate drug for psoriatic arthritis through bioinformatics analysis

Discovery of CLEC2B as a diagnostic biomarker and screening of celastrol as a candidate drug for psoriatic arthritis through bioinformatics analysis

Abstract Background Psoriatic arthritis (PSA) is a chronic, immune-mediated inflammatory joint disease that is liked to mortality due to cardiovascular disease. Diagnostic markers and effective therapeutic options for PSA remain limited due to the lack of understanding of the pathogenesis. We aimed...

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Bibliographic Details
Main Authors: Min Niu, Jingman Yuan, Meixi Yan, Ge Yang, Ziyi Yan, Xichao Yang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Psoriatic arthritis
Celastrol
Bioinformatics analysis
Molecular docking
Psoriasis
Online Access:https://doi.org/10.1186/s13018-023-03843-0

Internet

https://doi.org/10.1186/s13018-023-03843-0

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