Macrophage C/EBPδ Drives Gemcitabine, but Not 5-FU or Paclitaxel, Resistance of Pancreatic Cancer Cells in a Deoxycytidine-Dependent Manner
Treatment of pancreatic ductal adenocarcinoma (PDAC), a dismal disease with poor survival rates, is hampered by the high prevalence of chemotherapy resistance. Resistance is accompanied by macrophage infiltration into the tumor microenvironment, and infiltrated macrophages are key players in chemoth...
Główni autorzy: | , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
MDPI AG
2022-01-01
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Seria: | Biomedicines |
Hasła przedmiotowe: | |
Dostęp online: | https://www.mdpi.com/2227-9059/10/2/219 |