Macrophage C/EBPδ Drives Gemcitabine, but Not 5-FU or Paclitaxel, Resistance of Pancreatic Cancer Cells in a Deoxycytidine-Dependent Manner

Treatment of pancreatic ductal adenocarcinoma (PDAC), a dismal disease with poor survival rates, is hampered by the high prevalence of chemotherapy resistance. Resistance is accompanied by macrophage infiltration into the tumor microenvironment, and infiltrated macrophages are key players in chemoth...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: C. Arnold Spek, Hella L. Aberson, JanWillem Duitman
स्वरूप: लेख
भाषा:English
प्रकाशित: MDPI AG 2022-01-01
श्रृंखला:Biomedicines
विषय:
ऑनलाइन पहुंच:https://www.mdpi.com/2227-9059/10/2/219