Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function

Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function

Stratum corneum (SC) pH regulates skin barrier functions and elevated SC pH is an important factor in various inflammatory skin diseases. Acidic topical formulas have emerged as treatments for impaired skin barriers. Sodium proton exchanger 1 (NHE1) is an important factor in SC acidification. We inv...

Full description

Bibliographic Details
Main Authors: Seung-Won Jung, Gi Hyun Park, Eunjung Kim, Kang Min Yoo, Hea Won Kim, Jin Soo Lee, Min Youl Chang, Kyong-Oh Shin, Kyungho Park, Eung Ho Choi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
skin barrier
skin pH
sodium proton exchanger 1
<i>Melissa officinalis</i> leaf extract
rosmarinic acid
Online Access:https://www.mdpi.com/1422-0067/23/7/3910

Internet

https://www.mdpi.com/1422-0067/23/7/3910

Similar Items