Energy transfer between the nicotinamide nucleotide transhydrogenase and ATP synthase of Escherichia coli

Abstract Membrane bound nicotinamide nucleotide transhydrogenase (TH) catalyses the hydride transfer from NADH to NADP+. Under physiological conditions, this reaction is endergonic and must be energized by the pmf, coupled to transmembrane proton transport. Recent structures of transhydrogenase holo...

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Bibliographic Details
Main Authors: Simone Sandra Graf, Sangjin Hong, Philipp Müller, Robert Gennis, Christoph von Ballmoos
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00651-6