Characterization of two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, associated with the spread of IncP-2 megaplasmids in Pseudomonas aeruginosa

Characterization of two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, associated with the spread of IncP-2 megaplasmids in Pseudomonas aeruginosa

ABSTRACT This study aimed to characterize two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, and reveal the important role of the IncP-2 type megaplasmids in the spread of antimicrobial resistance (AMR) genes. VIM-84 and VIM-85 were encoded by two novel genes bla VIM-84 and bla VIM-85 which...

Full description

Bibliographic Details
Main Authors: Nanfei Wang, Tailong Lei, Yiwei Zhu, Yue Li, Heng Cai, Piaopiao Zhang, Sebastian Leptihn, Junxin Zhou, Huanhuan Ke, Bo Gao, Yu Feng, Xiaoting Hua, Tingting Qu
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
metallo-β-lactamase
VIM
megaplasmid
antimicrobial resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01544-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01544-23

Similar Items