Absence of early platelet increment in healthy mice during decitabine treatment

Abstract Treatment of myelodysplastic syndromes includes the administration of the hypomethylating agent decitabine. An early platelet response in decitabine-treated myelodysplastic syndrome patients is a predictor of overall survival. The effect of decitabine on megakaryocytes and the bone marrow,...

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Bibliographic Details
Main Authors: Juliane Baumann, Markus Spindler, Yannick Throm, Michael Lübbert, Markus Bender
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26821-8