Is there a link between genetic defects in the complement cascade and Porphyromonas gingivalis in Alzheimer’s disease?

Defects, as determined by Genome-Wide Association Studies (GWAS), in the complement cascade of innate immunity have been suggested to play a key role in Alzheimer’s disease (AD). These defective genes encode sub-component 1s (C1s), complement receptor 1, complement component 9, and clusterin, a flui...

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Dettagli Bibliografici
Autori principali: Ingar Olsen, Sim K Singhrao
Natura: Articolo
Lingua:English
Pubblicazione: Taylor & Francis Group 2020-01-01
Serie:Journal of Oral Microbiology
Soggetti:
Accesso online:http://dx.doi.org/10.1080/20002297.2019.1676486