Downregulation of salusins alleviates hypertrophic cardiomyopathy via attenuating oxidative stress and autophagy

Downregulation of salusins alleviates hypertrophic cardiomyopathy via attenuating oxidative stress and autophagy

Abstract Introduction Salusins, which are translated from the alternatively spliced mRNA of torsin family 2 member A (TOR2A), play a vital role in regulation of various cardiovascular diseases. However, it remains unclear precisely regarding their roles in hypertrophic cardiomyopathy (HCM). Therefor...

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Bibliographic Details
Main Authors: Jing-Yi Dang, Wei Zhang, Yi Chu, Jiang-Hong Chen, Zhao-Le Ji, Pin Feng
Format: Article
Language:English
Published: BMC 2024-02-01
Series:European Journal of Medical Research
Subjects:
Salusin
Hypertrophic cardiomyopathy
Fibrosis
Oxidative stress
Autophagy
Online Access:https://doi.org/10.1186/s40001-024-01676-z

Internet

https://doi.org/10.1186/s40001-024-01676-z

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