The circular RNA circATP8B(2) regulates ROS production and antiviral immunity in Drosophila

Summary: We identified and validated a collection of circular RNAs (circRNAs) in Drosophila melanogaster. We show that depletion of the pro-viral circRNA circATP8B(2), but not its linear siblings, compromises viral infection both in cultured Drosophila cells and in vivo. In addition, circATP8B(2) is...

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Bibliographic Details
Main Authors: Weihong Liang, Wei Liu, Xiao-Peng Xiong, Jennifer W. Li, Jian-Liang Li, Ranjan J. Perera, Rui Zhou
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724003012