First use of triply labelled water analysis for energy expenditure measurements in mice

Abstract The doubly labelled water (DLW) method is widely used to determine energy expenditure. In this work, we demonstrate the addition of the third stable isotope, 17O, to turn it into triply labelled water (TLW), using the three isotopes measurement of optical spectrometry. We performed TLW (2H,...

Full description

Bibliographic Details
Main Authors: Xing Wang, Dehuang Kong, Gertjan van Dijk, Harro A. J. Meijer
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10377-8