Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development.

Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development.

Neuronal output requires a concerted balance between excitatory and inhibitory (I/E) input. Like other circuits, inhibitory synaptogenesis in the retina precedes excitatory synaptogenesis. How then do neurons attain their mature balance of I/E ratios despite temporal offset in synaptogenesis? To dir...

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Bibliographic Details
Main Authors: Adam Bleckert, Edward D Parker, Yunhee Kang, Raika Pancaroglu, Florentina Soto, Renate Lewis, Ann Marie Craig, Rachel O L Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724919?pdf=render

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http://europepmc.org/articles/PMC3724919?pdf=render

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