Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development.

Neuronal output requires a concerted balance between excitatory and inhibitory (I/E) input. Like other circuits, inhibitory synaptogenesis in the retina precedes excitatory synaptogenesis. How then do neurons attain their mature balance of I/E ratios despite temporal offset in synaptogenesis? To dir...

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Bibliographic Details
Main Authors: Adam Bleckert, Edward D Parker, Yunhee Kang, Raika Pancaroglu, Florentina Soto, Renate Lewis, Ann Marie Craig, Rachel O L Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724919?pdf=render

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