High-throughput analysis of tissue microarrays using automated desorption electrospray ionization mass spectrometry

Abstract Tissue microarrays (TMAs) are commonly used for the rapid analysis of large numbers of tissue samples, often in morphological assessments but increasingly in spectroscopic analysis, where specific molecular markers are targeted via immunostaining. Here we report the use of an automated high...

Full description

Bibliographic Details
Main Authors: Nicolás M. Morato, Hannah Marie Brown, Diogo Garcia, Erik H. Middlebrooks, Mark Jentoft, Kaisorn Chaichana, Alfredo Quiñones-Hinojosa, R. Graham Cooks
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22924-4