Quantifying the Determinants of Evolutionary Dynamics Leading to Drug Resistance.

The emergence of drug resistant pathogens is a serious public health problem. It is a long-standing goal to predict rates of resistance evolution and design optimal treatment strategies accordingly. To this end, it is crucial to reveal the underlying causes of drug-specific differences in the evolut...

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Bibliographic Details
Main Authors: Guillaume Chevereau, Marta Dravecká, Tugce Batur, Aysegul Guvenek, Dilay Hazal Ayhan, Erdal Toprak, Tobias Bollenbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4651364?pdf=render