Quantifying the Determinants of Evolutionary Dynamics Leading to Drug Resistance.
The emergence of drug resistant pathogens is a serious public health problem. It is a long-standing goal to predict rates of resistance evolution and design optimal treatment strategies accordingly. To this end, it is crucial to reveal the underlying causes of drug-specific differences in the evolut...
Main Authors: | Guillaume Chevereau, Marta Dravecká, Tugce Batur, Aysegul Guvenek, Dilay Hazal Ayhan, Erdal Toprak, Tobias Bollenbach |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC4651364?pdf=render |
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