Sizes and shapes of perivascular spaces surrounding murine pial arteries

Abstract Background Flow of cerebrospinal fluid (CSF) through brain perivascular spaces (PVSs) is essential for the clearance of interstitial metabolic waste products whose accumulation and aggregation is a key mechanism of pathogenesis in many diseases. The PVS geometry has important implications f...

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Bibliographic Details
Main Authors: Nikola Raicevic, Jarod M. Forer, Antonio Ladrón-de-Guevara, Ting Du, Maiken Nedergaard, Douglas H. Kelley, Kimberly Boster
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-023-00454-z