Human epidermal growth factor receptor 2 (HER2)-specific chimeric antigen receptor (CAR) for tumor immunotherapy; recent progress

Human epidermal growth factor receptor 2 (HER2)-specific chimeric antigen receptor (CAR) for tumor immunotherapy; recent progress

Abstract Due to the overexpression or amplification of human epidermal growth factor receptor 2 (HER2) with poor prognosis in a myriad of human tumors, recent studies have focused on HER2-targeted therapies. Deregulation in HER2 signaling pathways is accompanied by sustained tumor cells growth conco...

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Bibliographic Details
Main Authors: Hendrik Setia Budi, Firdaus Nuri Ahmad, Harun Achmad, Mohammad Javed Ansari, Maria Vladimirovna Mikhailova, Wanich Suksatan, Supat Chupradit, Navid Shomali, Faroogh Marofi
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Stem Cell Research & Therapy
Subjects:
Chimeric antigen receptor (CAR)
Human epidermal growth factor receptor 2 (HER2)
CAR-T cell
Solid tumors
Tumor microenvironment (TME)
Online Access:https://doi.org/10.1186/s13287-022-02719-0

Internet

https://doi.org/10.1186/s13287-022-02719-0

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