Urine microRNA Profiling Displays miR-125a Dysregulation in Children with Fragile X Syndrome

Urine microRNA Profiling Displays miR-125a Dysregulation in Children with Fragile X Syndrome

A triplet repeat expansion leading to transcriptional silencing of the <i>FMR1</i> gene results in fragile X syndrome (FXS), which is a common cause of inherited intellectual disability and autism. Phenotypic variation requires personalized treatment approaches and hampers clinical trial...

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Bibliographic Details
Main Authors: Noora Putkonen, Asta Laiho, Doug Ethell, Juha Pursiheimo, Anna-Kaisa Anttonen, Juho Pitkonen, Adriana M. Gentile, Yolanda de Diego-Otero, Maija L. Castrén
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
disease biomarker
urine mirna
fragile x syndrome
autism
mir-125a
Online Access:https://www.mdpi.com/2073-4409/9/2/289

Internet

https://www.mdpi.com/2073-4409/9/2/289

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