HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes

HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes

High mobility group box-1 (HMGB1), a nonhistone chromatin DNA-binding protein, is released from neurons into the extracellular space under ischemic, hemorrhagic, and traumatic insults. However, the details of the time-dependent translocation of HMGB1 and the subcellular localization of HMGB1 through...

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Bibliographic Details
Main Authors: Dengli Wang, Keyue Liu, Yusuke Fukuyasu, Kiyoshi Teshigawara, Li Fu, Hidenori Wake, Aiji Ohtsuka, Masahiro Nishibori
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
middle cerebral artery occlusion
high-mobility group box 1
subcellular localization and subcellular organelle
Online Access:https://www.mdpi.com/2073-4409/9/3/643

Internet

https://www.mdpi.com/2073-4409/9/3/643

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