The testosterone-dependent and independent transcriptional networks in the hypothalamus of <it>Gpr54 </it>and <it>Kiss1 </it>knockout male mice are not fully equivalent

The testosterone-dependent and independent transcriptional networks in the hypothalamus of <it>Gpr54 </it>and <it>Kiss1 </it>knockout male mice are not fully equivalent

<p>Abstract</p> <p>Background</p> <p>Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have y...

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Main Authors: Sutcliffe Margaret, Poon Steven, Turashvili Gulisa, Yap Damian, Ruiz de Algara Teresa, McKinney Steven, d'Anglemont de Tassigny Xavier, Prentice Leah M, Allard Pat, Burleigh Angela, Fee John, Huntsman David G, Colledge William H, Aparicio Samuel AJ
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/209

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http://www.biomedcentral.com/1471-2164/12/209

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