Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

Abstract Background Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognise bacterial metabolites presented by MHC class I-related protein 1 (MR1). Bacterial dysbiosis has been implicated in auto-inflammatory disease development. We investigated MAIT cells in early, untrea...

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Bibliographic Details
Main Authors: Hester Koppejan, Diahann T. S. L. Jansen, Marjolijn Hameetman, Ranjeny Thomas, Rene E. M. Toes, Floris A. van Gaalen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Spondyloarthritis
Mucosal-associated invariant T cells
CD161
Online Access:http://link.springer.com/article/10.1186/s13075-018-1799-1

Internet

http://link.springer.com/article/10.1186/s13075-018-1799-1

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