Exploring secretory proteome and cytokine kinetic of human peripheral blood mononuclear cells exposed to methicillin-resistant Staphylococcus aureus biofilms and planktonic bacteria

Exploring secretory proteome and cytokine kinetic of human peripheral blood mononuclear cells exposed to methicillin-resistant Staphylococcus aureus biofilms and planktonic bacteria

Staphylococcus aureus is a highly successful pathogen infecting various body parts and forming biofilms on natural and artificial surfaces resulting in difficult-to-treat and chronic infections. We investigated the secreted cytokines and proteomes of isolated peripheral blood mononuclear cells (PBMC...

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Bibliographic Details
Main Authors: Reza Gheitasi, Daniela Röll, Mario M. Müller, Mohadeseh Naseri, Rainer König, Hortense Slevogt, Mathias W. Pletz, Oliwia Makarewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
biomarkers
machine learning
chronic infections
proteomics
artificial neural networks
cytokine profiling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1334616/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1334616/full

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