Pre-operative anxiolysis in children through a combined pharmacological therapy with hydroxyzine and a non-pharmacological distraction technique with a clown (SONRISA): study protocol for randomised double-blind clinical trial

Abstract Background Surgery can generate significant stress and anxiety in up to 70% of the paediatric population. There are several pharmacological and non-pharmacological strategies to reduce pre-operative anxiety in children, however, they have several side effects and the available information a...

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Main Authors: Esther Aleo Luján, Amanda Lopez-Picado, Ana Rivas, Belén Joyanes Abancens, Marina Laura Rodríguez Rojo, Patricia Fernández García, Carmen Soto Beauregard, Jaime Rodríguez Alarcón, Carlos González Perrino, Borja San Pedro de Urquiza, Eva Arias, Diamelis Rodriguez, Carmen Esteban Polonio, Maria José Torrejón
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-019-3906-2