Circulating tumor DNA in clinical trials for solid tumors: Challenges and current applications

Circulating tumor DNA in clinical trials for solid tumors: Challenges and current applications

Tumor derived biomarkers including circulating tumor DNA (ctDNA) and/or circulating tumors cells (CTCs) may be detected and quantified through liquid biopsy (LB). ctDNA analysis through LB is a validated tool for monitoring response to systemic treatment and detecting molecular mechanisms of resista...

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Bibliographic Details
Main Authors: Claudia Parisi, Marco Tagliamento, Laila Belcaid, Mihaela Aldea, Arnaud Bayle, Jordi Remon-Masip, Antoine Italiano, David Planchard, Benjamin Besse, Fabrice Barlesi
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:The Journal of Liquid Biopsy
Subjects:
ctDNA
Liquid biopsy
Cancer
Clinical trials
Molecular genotyping
Early detection
Online Access:http://www.sciencedirect.com/science/article/pii/S2950195423000073

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http://www.sciencedirect.com/science/article/pii/S2950195423000073

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