Glycine Supplementation in Obesity Worsens Glucose Intolerance through Enhanced Liver Gluconeogenesis

Interactions between mitochondria and the endoplasmic reticulum, known as MAMs, are altered in the liver in obesity, which contributes to disruption of the insulin signaling pathway. In addition, the plasma level of glycine is decreased in obesity, and the decrease is strongly correlated with the se...

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Bibliographic Details
Main Authors: Anaïs Alves, Frédéric Lamarche, Rémy Lefebvre, Eva Drevet Mulard, Arthur Bassot, Stéphanie Chanon, Emmanuelle Loizon, Claudie Pinteur, Aline Maria Nunes de Lira Gomes Bloise, Murielle Godet, Gilles J. P. Rautureau, Baptiste Panthu, Béatrice Morio
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/1/96