Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1

Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1

ABSTRACT The prevalence of drug-resistant Mycobacterium tuberculosis infections has prompted extensive efforts to exploit new drug targets in this globally important pathogen. ClpC1, the unfoldase component of the essential ClpC1P1P2 protease, has emerged as one particularly promising antibacterial...

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Bibliographic Details
Main Authors: Emmanuel C. Ogbonna, Henry R. Anderson, Patrick C. Beardslee, Priyanka Bheemreddy, Karl R. Schmitz
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Clp protease
Mycobacterium
interactome
proteolysis
proteomics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04548-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04548-22

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