Short Double-Stranded DNA (≤40-bp) Affects Repair Pathway Choice
To repair ionizing radiation (IR)-induced double strand breaks (DSBs), mammalian cells primarily use canonical non-homologous end-joining (cNHEJ), the homologous recombination (HR) pathway, and the alternative non-homologous end-joining (aEJ) as a backup. These pathways function either compensativel...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/14/11836 |