Short Double-Stranded DNA (≤40-bp) Affects Repair Pathway Choice
To repair ionizing radiation (IR)-induced double strand breaks (DSBs), mammalian cells primarily use canonical non-homologous end-joining (cNHEJ), the homologous recombination (HR) pathway, and the alternative non-homologous end-joining (aEJ) as a backup. These pathways function either compensativel...
Main Authors: | Zhentian Li, Ya Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/14/11836 |
Similar Items
-
Beta HPV Deregulates Double-Strand Break Repair
by: Changkun Hu, et al.
Published: (2022-04-01) -
Double-Stranded Break Repair in Mammalian Cells and Precise Genome Editing
by: Akhtar Ali, et al.
Published: (2022-04-01) -
DNA Double-Strand Break Repairs and Their Application in Plant DNA Integration
by: Hexi Shen, et al.
Published: (2022-02-01) -
Arsenite Impairs BRCA1-Dependent DNA Double-Strand Break Repair, a Mechanism Potentially Contributing to Genomic Instability
by: Tizia Matthäus, et al.
Published: (2023-09-01) -
LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells
by: Bo-Ruei Chen, et al.
Published: (2021-09-01)