Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports

Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports

Lineage switch is a rare phenomenon in which a transition from lymphoid to myeloid was observed in relapse of acute leukemia, or vice versa. This paper presents the four clinical case reports of acute lymphoblastic leukemia with MLL gene rearrangement (KMT2A) with myeloid phenotype in relapse.

Bibliographic Details
Main Authors: E. A. Zerkalenkova, O. I. Illarionova, A. N. Kazakova, N. I. Ponomareva, L. V. Baydun, E. Yu. Osipova, M. E. Dubrovina, A. M. Popov, T. V. Konyukhova, S. A. Plyasunova, N. V. Myakova, A. A. Maschan, Yu. V. Olshanskaya
Format: Article
Language:Russian
Published: ABV-press 2016-08-01
Series:Онкогематология
Subjects:
acute lymphoblastic leukemia
acute myeloid leukemia
lineage switch
kmt2a gene rearrangement
immunophenotyping
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/193

Internet

https://oncohematology.abvpress.ru/ongm/article/view/193

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