Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer

Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer

Abstract Background Although parity and age at first pregnancy are among the most known extrinsic factors that modulate breast cancer risk, their impact on the biology of subsequent breast cancer has never been explored in depth. Recent data suggest that pregnancy-induced tumor protection is differe...

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Bibliographic Details
Main Authors: Bastien Nguyen, David Venet, Matteo Lambertini, Christine Desmedt, Roberto Salgado, Hugo Mark Horlings, Françoise Rothé, Christos Sotiriou
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Pregnancy
Genomics
SCNAs
Mutational landscape
Whole genome sequencing
Online Access:http://link.springer.com/article/10.1186/s13058-019-1111-6

Internet

http://link.springer.com/article/10.1186/s13058-019-1111-6

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