A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection

A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection

Developing drugs to treat the toxic effects of lethal toxin (LT) and edema toxin (ET) produced by B. anthracis is of global interest. We utilized a computational approach to score 474 drugs/compounds for their ability to reverse the toxic effects of anthrax toxins. For each toxin or drug/compound, w...

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Bibliographic Details
Main Authors: Jane P. F. Bai, Theodore Sakellaropoulos, Leonidas G. Alexopoulos
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Toxins
Subjects:
drug repurposing
anthrax
computation
signaling network of a drug
Online Access:http://www.mdpi.com/2072-6651/9/3/99

Internet

http://www.mdpi.com/2072-6651/9/3/99

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