Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone

Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone

Mycobacterium ulcerans is the causal agent of Buruli ulcer, a chronic infectious disease and the third most common mycobacterial disease worldwide. Without early treatment, M. ulcerans provokes massive skin ulcers, caused by the mycolactone toxin, its main virulence factor. However, spontaneous heal...

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Bibliographic Details
Main Authors: Marie Robbe-Saule, Mélanie Foulon, Isabelle Poncin, Lucille Esnault, Hugo Varet, Rachel Legendre, Alban Besnard, Anna E. Grzegorzewicz, Mary Jackson, Stéphane Canaan, Laurent Marsollier, Estelle Marion
Format: Article
Language:English
Published: Taylor & Francis Group 2021-12-01
Series:Virulence
Subjects:
mycobacterium ulcerans
host-bacterium interaction
mycolactone
rna-sequencing
metabolism
Online Access:http://dx.doi.org/10.1080/21505594.2021.1929749

Internet

http://dx.doi.org/10.1080/21505594.2021.1929749

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