Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone
Mycobacterium ulcerans is the causal agent of Buruli ulcer, a chronic infectious disease and the third most common mycobacterial disease worldwide. Without early treatment, M. ulcerans provokes massive skin ulcers, caused by the mycolactone toxin, its main virulence factor. However, spontaneous heal...
Main Authors: | Marie Robbe-Saule, Mélanie Foulon, Isabelle Poncin, Lucille Esnault, Hugo Varet, Rachel Legendre, Alban Besnard, Anna E. Grzegorzewicz, Mary Jackson, Stéphane Canaan, Laurent Marsollier, Estelle Marion |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-12-01
|
Series: | Virulence |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/21505594.2021.1929749 |
Similar Items
-
The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis
by: Louise Tzung-Harn Hsieh, et al.
Published: (2025-02-01) -
Rate of Production of Inflammatory Cytokines TNF and IL- by Peripheral Blood Mononuclear Cells Stimulated with Mycolactone
by: P Mohajeri, et al.
Published: (2010-08-01) -
Buruli ulcer: The Efficacy of Innate Immune Defense May Be a Key Determinant for the Outcome of Infection With Mycobacterium ulcerans
by: Katharina Röltgen, et al.
Published: (2020-05-01) -
Alternative boronic acids in the detection of Mycolactone A/B using the thin layer chromatography (f-TLC) method for diagnosis of Buruli ulcer
by: Gideon A. Akolgo, et al.
Published: (2023-07-01) -
From Bacterial Toxin to Therapeutic Agent: The Unexpected Fate of Mycolactone
by: Daniela Ricci, et al.
Published: (2023-05-01)