Deferiprone–resveratrol hybrid attenuates iron accumulation, oxidative stress, and antioxidant defenses in iron-loaded human Huh7 hepatic cells

Deferiprone–resveratrol hybrid attenuates iron accumulation, oxidative stress, and antioxidant defenses in iron-loaded human Huh7 hepatic cells

Chronic liver diseases are complications of thalassemia with iron overload. Iron chelators are required to remove excessive iron, and antioxidants are supplemented to diminish harmful reactive oxygen species (ROS), purposing to ameliorate oxidative liver damage and dysfunctions. The deferiprone–resv...

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Bibliographic Details
Main Authors: Jin Li, Pimpisid Koonyosying, Woranontee Korsieporn, Narisara Paradee, Nuntouchaporn Hutachok, Honghong Xu, Yongmin Ma, Hataichanok Chuljerm, Somdet Srichairatanakool
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
iron chelator
deferiprone
resveratrol
antioxidant
hepatoprotective
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1364261/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2024.1364261/full

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