Novel inverse agonists for the orphan G protein-coupled receptor 6

The orphan G protein-coupled receptor 6 (GPR6) displays unique promise as a therapeutic target for the treatment of neuropsychiatric disorders due to its high expression in the striatopallidal neurons of the basal ganglia. GPR6, along with closely related orphan receptors GPR3 and GPR12, are phyloge...

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Bibliographic Details
Main Authors: Alyssa S. Laun, Sarah H. Shrader, Zhao-Hui Song
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018337642