The distinct effects of P18 overexpression on different stages of hematopoiesis involve TGF-β and NF-κB signaling

The distinct effects of P18 overexpression on different stages of hematopoiesis involve TGF-β and NF-κB signaling

Abstract Deficiency of P18 can significantly improve the self-renewal potential of hematopoietic stem cells (HSC) and the success of long-term engraftment. However, the effects of P18 overexpression, which is involved in the inhibitory effects of RUNX1b at the early stage of hematopoiesis, have not...

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Main Authors: Danying Yi, Lijiao Zhu, Yuanling Liu, Jiahui Zeng, Jing Chang, Wencui Sun, Jiawen Teng, Yonggang Zhang, Yong Dong, Xu Pan, Yijin Chen, Ya Zhou, Mowen Lai, Qiongxiu Zhou, Jiaxin Liu, Bo Chen, Feng Ma
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03263-2

Internet

https://doi.org/10.1038/s41598-021-03263-2

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