The distinct effects of P18 overexpression on different stages of hematopoiesis involve TGF-β and NF-κB signaling
Abstract Deficiency of P18 can significantly improve the self-renewal potential of hematopoietic stem cells (HSC) and the success of long-term engraftment. However, the effects of P18 overexpression, which is involved in the inhibitory effects of RUNX1b at the early stage of hematopoiesis, have not...
Main Authors: | Danying Yi, Lijiao Zhu, Yuanling Liu, Jiahui Zeng, Jing Chang, Wencui Sun, Jiawen Teng, Yonggang Zhang, Yong Dong, Xu Pan, Yijin Chen, Ya Zhou, Mowen Lai, Qiongxiu Zhou, Jiaxin Liu, Bo Chen, Feng Ma |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-03263-2 |
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