Transport, Metabolism, and Function of Thyroid Hormones in the Developing Mammalian Brain

Ever since the discovery of thyroid hormone deficiency as the primary cause of cretinism in the second half of the 19th century, the crucial role of thyroid hormone (TH) signaling in embryonic brain development has been established. However, the biological understanding of TH function in brain forma...

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Bibliographic Details
Main Authors: Barbara K. Stepien, Wieland B. Huttner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00209/full